Comfort Formula®

Anti depressant

Today depression is the most prevalent diseases and the most common psychiatric disorders, especially in populated urban communities due to social and economic problems. Depression can reduce the personal and social performance and lead to dissatisfaction with life.

Changes in mood, lack of concentration, feelings of helplessness and hopelessness, loss of interest in daily activities, appetite or weight changes, sleep changes, anger or irritability, loss of energy and unexplained aches and pains are some symptoms of depression. Long-term use of common antidepressant drugs may cause cardiovascular complications, impaired memory and concentration, dizziness, sexual dysfunction, weight loss or weight gain and drug dependence.




  • Helps treat depression
  • Reduces anxiety
  • Helps to alleviate tension headache and migraine
  • Relieves behavioral symptoms associated with PMS
  • Relieves the psychological symptoms of menopause
  • Sleep disorder



Hypericum perforatum

Common name: St. John’s wort 


St. John’s wort is a plant with yellow flowers whose medicinal uses were first recorded in ancient Greece. Historically, it has been used for centuries to treat mental disorders and nerve pain. Today St. John’s wort is used as a folk or traditional remedy for depression, anxiety and sleep disorders. Now it is the number one treatment in Germany and has been extensively studied by Commission E, the scientific advisory panel to the German government.

 It contains several chemicals, including hypericin, hyperforin, and pseudohypericin, which are thought to be the major sources of antidepressant activity.

In several studies of laboratory animals and humans, one or more of the chemicals in St. John’s wort appeared to delay or decrease re-absorption of the neurotransmitters dopamine, norepinephrine, and serotonin by nerve cells.

Ordinarily, once the message has been delivered, neurotransmitters are re-absorbed and inactivated by the cells that released them. Chemicals in St. John’s wort may keep more of these antidepressant neurotransmitters available for the body to utilise. Multiple studies have shown that St. John’s wort may be effective in relieving mild to moderate depression, although maximum antidepressant effects may take several weeks to develop.

St. John’s Wort is an MAO inhibitor and should not be used with alcohol and some other foods. It has also been studied for the treatment of other emotional disorders such as anxiety, obsessive-compulsive disorder (OCD), menopausal mood swings, and premenstrual syndrome.

Combining St. John’s wort with certain antidepressants can lead to a potentially life-threatening increase of serotonin, a brain chemical targeted by antidepressants.

Combining St. John’s wort and certain antidepressants can lead to a potentially life-threatening increase in serotonin levels—a condition called serotonin syndrome.

Supplement Facts
Amount per tablet RDA%
St John’s Wort 333 mg *


30 Film Coated Tablets


Take one tablet daily with meal



Patients with alzheimer, anesthesia, bipolar disorder, depression, infertility, schizophernia and  therapeutic UV treatment should consult physician before using.

Pregnancy and Lactation:

St John’s wort preparations should not be used during pregnancy and lactation.

Pregnant or lactating women should consult a physician before using this product.


Patients who take 5- HTI agonists, alprazolom, amitriptyline, anti depressant drugs, barbiturates, clopidogrel, contraceptive drugs, cyclosporine, cytochorome P450, dextromethorphan, digoxin, fenfluramine, fexofenadine, imatinib, irinotecan, meperidine, monoamin oxidase inhibitors, narcotic drugs, nefazodone, non nucleoside reverse transcriptase inhibitors, nortriptyline, paroxetine, P-glycoprotein substrates, phenobarbital, phenprocoumon, phenytoin, photosensitizing drugs, protease inhibitator, reserpin, sertraline, simvastatin, tacrolimus, theophylline, tramadole and warfarin, should consult physician before using.

Adverse effects:

No adverse effects have been reported to date.         
This product includes extract of St. John’s worth, which in rare case can cause hyper sensitivity.


Always read the label and use only as directed.           
Keep out of reach of children.         

Keep in a cool (below 25° C) and dry place, away from direct sunlight.