Helps normal liver function
Liver is the second largest organ in the body and perform a number of essential functions related to digestion, metabolism and immunity. The major function of liver includes the production of bile. It also metabolizes drugs and detoxifies toxins.
- Liver and gallbladder complaints
- Regenerates hepatocells
- Protects liver cells against oxidative damage and toxins
- Lipid-reducing effect
Silybum marianum (L.)
Common name: Milk Thistle
An extract of milk thistle seed is the primary botanical preparation used in Europe for supporting a healthy liver and treating liver disease. Both oral and injectable preparations are used. The injectables are highly regarded as an effective treatment against poisoning with the potentially deadly death angel mushroom, Amanita phalloides.
The Active ingredients are mostly flavonoids, steroids and organic acids. The chief components are Silymarin and then silybin A, silybin B, isosilybin, silychristin and silydianin.
The drug is used for toxic liver damage, functional disorders of liver and gallbladder including jaundice, gallbladder, colic and adjunctive treatment in chronic inflammatory liver disease, none-alcoholic fatty liver and hepatic cirrhosis.
The hepatoprotective activity of the seed is from silymarin, in particular, silychristin and silydianin. The compounds seem to inhibit the entrance of toxins and block toxin binding sites through alteration of the liver cell’s outer membrane. Silibinin decreases production of superoxide radicals and nitric oxide. Silibinin also inhibits leukotriene formation by the Kupffer cells. Silymarin increases glutathione production by the liver, intestines and stomach. Glutathione is used for detoxification cells in the liver.
The seed exerts an anti-inflammatory effect through inhibition of leukotriene production by silymarin. Silibinin and silychristin demonstrated remarkable stimulatory effects on proliferation rate, biosynthesis of protein and DNA, and activity of the enzyme lactate dehydrogenase in kidney cells.
Liver Regenerative Effects
Silymarin stimulates RNA polymerase I in the cell nucleus of the hepatocytes, resulting in an increase of ribosomal protein synthesis and the regenerative ability of the liver.
Common name: Globe Artichoke
Artichoke has been employed as a bile stimulant and diuretic. As a traditional medicine, artichoke has been used primarily for enhancing liver and gallbladder function. Among traditional healers, artichoke has been used to treat chronic liver and gall bladder diseases, jaundice, hepatitis, arteriosclerosis and high cholesterol. Italian scientists isolated a compound from artichoke leaf called cynarin which was used as a drug to stimulate the liver and gall bladder and to treat elevated cholesterol.
The Active ingredients are caffeic acid derivatives mainly cynarin. Cynarin which is responsible for bitter taste of the herb considered one of artichoke’s main biologically active chemicals. It occurs in the highest concentration in the leaves of the plant. Other documented active chemicals include flavonoids, sesquiterpene lactones and polyphenols. Artichoke is used for dyspeptic problems, prophylactic treatment against the return of gallstones and also has lipid-reducing and hepato stimulating effect.
It belongs to the B-complex family and helps fat metabolism along with choline. It prevents fatty build up in the liver and needs for cholesterol and some phosphatides metabolism.
Choline is a vitamin-like essential nutrient and a methyl donor involved in many physiological processes, including normal metabolism and transport of lipids and methylation reactions. Choline deficiency causes abnormal deposition of fat in the liver, which results in a condition called nonalcoholic fatty liver disease.
It is used to prevent liver damage in acetaminophen poisoning and also used for treating liver disorders. It treats alcoholism and radiation side effects.
It is a non protein amino acid which used to treat liver disease (hepatitis).Taurine has antioxidant activity. It has putative hypocholesterolemic and detoxifying activities. The hypocholesterolemic effect of taurine is due to the stimulation of bile acid synthesis and enhancement of cholesterol 7 alpha-hydroxylase activity.
|Amount per tablet||RDA%|
|Milk Thistle||42.86 mg||*|
|Globe Artichoke||120 mg||*|
|Choline bitartrate||50 mg||10|
30 Film Coated Tablets
Take one tablet daily with meal.
No contraindications have been reported to date.
This product includes extracts of herb as below:
Milk Thistle: Patients with allergic reaction, breast cancer, uterine cancer, ovarian cancer, endometriosis and uterine fibroids, use cautiously and should consult a physician before using.
Globe Artichoke: Patients with bile duct obstruction and gall stones use cautiously and should consult a physician before using.
Pregnancy and Lactation:
This product is safe to use by pregnant or lactating women.
Pregnant or lactating women should consult a physician before using this product.
No interaction with other medicinal products has been reported to date.
This product includes extract of Milk thistle:
People who take cytochrome P450, amitriptyline, diazepam, verapamil, warfarin, estrogen drugs and glucuronidated drugs should consult a physician before using.
No adverse effect has been reported to date.
This product includes extracts of herb as below:
Milk Thistle: pure extract of Milk thistle can cause laxative effects, nausea, diarrhea, dyspepsia, flatulence, abdominal bloating, fullness or pain, pruritus, rash, urticaria, eczema and anaphylaxis.
Globe Artichoke: pure extract Globe artichoke can cause flatulence and dermatitis.
Always read the label and use only as directed.
keep out of reach of children.
Keep in a cool (below 25° C) and dry place, away from direct sunlight.